The calcium paradox - What should we have to fear?

نویسندگان

  • Marcos Aurélio Barboza de Oliveira
  • Antônio Carlos Brandi
  • Carlos Alberto dos Santos
  • Paulo Henrique Husseni Botelho
  • José Luís Lasso Cortez
  • Gilberto Goissis
  • Domingo Marcolino Braile
چکیده

The calcium paradox was first mentioned in 1966 by Zimmerman et al. Thereafter gained great interest from the scientific community due to the fact of the absence of calcium ions in heart muscle cells produce damage similar to ischemia-reperfusion. Although not all known mechanisms involved in cellular injury in the calcium paradox intercellular connection maintained only by nexus seems to have a key role in cellular fragmentation. The addition of small concentrations of calcium, calcium channel blockers, and hyponatraemia hypothermia are important to prevent any cellular damage during reperfusion solutions with physiological concentration of calcium.

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عنوان ژورنال:

دوره 29  شماره 

صفحات  -

تاریخ انتشار 2014